SURFACE-FUNCTIONALIZED PARTICLES

Funktionelle Gruppen
 
In medical diagnostics, pharmaceutical industry, biotechnology, molecular biology, analytics, etc. multifunctional polymer particles with tailored surface properties are required to a growing extent. In recent years, microParticles GmbH successfully accomplished the development of functionalized polystyrene-, PMMA-, silica-, and melamine resin particles. Innovative strategies and preparation techniques, such as
  • chemical derivatization of the polymer surfaces,
  • sol-gel processes,
  • use of functionalized monomers,
  • surface polymerization in organic and aqueous media,
  • modification of particle surfaces by self-assembly (SAMs),
  • nanostructured surface coatings
led to the linkage of a variety of functional groups to the surface of particles, made from different materials. The adjacent figure illustrates available functionalities. Particular emphasis is placed on carboxylated polymer beads, especially on melamine resin basis. With loadings of up to 1000 µmole COOH/g, these particles show excellent monodispersity, high mechanical strength and chemical resistance, low non-specific protein adsorption, and good colloidal stability over a wide range of pH values and electrolyte concentrations. Mercapto- and amino-functionalized particles also belong to our product spectrum. Upon request, modification with sulfonic acid, maleimid, epoxy, or hydroxyl groups is possible.

Surface-functionalized particles:
(Click "Table"-buttons to view the complete particle spectrum or enter your desired particle diameter in µm.)
  • Carboxylated MF particles (MF-COOH)
  • Carboxylated PMMA particles (PMMA-COOH)
  • Carboxylated PS particles (PS-COOH)
  • Carboxylated and fluorescently labeled MF particles (MF-Fluo-COOH)
  • Carboxylated Silica particles (SiO2-COOH)
  • Aminated Silica particles (SiO2-NH2)

Pack sizes:

  • aqueous dispersions (100 mg/ml): 5 ml, 10 ml, 15 ml (MF-, PS-, PMMA-COOH)
  • aqueous dispersions (25 mg/ml): 5 ml, 10 ml, 15 ml (MF-Fluo-COOH)
  • aqueous dispersions (50 mg/ml): 5 ml, 10 ml, 15 ml (SiO2-COOH, SiO2-NH2)

-> Inquiries for other materials and diameters, than listed in the product tables are welcome.


Back to microParticles homepage or Product Palette